Physicians and nurses often benefit from support on how to discuss research-related issues with patients and families. Topics such as patient protections, IRBs, the research process, and benefits of study participation are essential to ensure patients and families have adequate information to fully consider study participation. PCRG produces a Pre-study Information Folder for sites to use during discussions with prospective subjects and family that facilitates the discussion and provides contextual information about research related issues.

Each folder includes the informed consent form, the study brochure, and an overview of the investigational product and related issues. Additionally, information is provided about how research works, patient protections and other adjunct information to aid patient deliberation. PCRG develops all materials for inclusion in the folder, as well as produces and distributes folders to each clinical site.